Research Associate Position in Cell and Molecular Biophysics at the School of Biomedical Sciences, King’s College London, UK 2012
About Scholarship: A Research Associate post is available in the Eggert group at the Randall Division of Cell and Molecular Biophysics, King’s College London. How cells regulate and execute cytokinesis, the final step of cell division, remain major unsolved questions in biology.
The goal of our laboratory is to use chemical biology approaches to address unanswered mechanistic questions by studying cytokinesis at the process, pathway and protein levels.This post will focus on investigating how membrane trafficking participates in cytokinesis and how cells transmit cues from the cellular environment to the cell division machinery. We recently reported a small molecule inhibitor of endocytic sorting and cytokinesis (Zhang et al., PNAS, 2012).
This small molecule, Prazosin, exerts its effects through a G-protein coupled receptor (GPCR), the dopamine receptor 3. We have also shown that other GPCRs participate in cytokinesis. The goal of the postdoctoral researcher working on this project will be to use a combination of RNAi and small molecule treatments to dissect the role of membrane-based signal transduction during cytokinesis. This is an interdisciplinary project, in which different aspects will be emphasised according to the researcher’s experience and interest. It includes chemical biology, systems biology-based approaches to study GPCR signalling, biochemistry, and/or cell biology and imaging.
Cover: The appointment will be made, dependent on relevant qualifications, within the Grade 6 scale, currently £31,020 to £33,884, per annum plus £2,323 per annum London Allowance.
Duration: Fixed term contract for 2 years
Study Subject: Cell and Molecular Biophysics
Course Level: Research
Scholarship by: King’s College London
Scholarship can be taken at: UK
-International applications will be considered for this position.
-BSc in a biological or chemical discipline.
-PhD in a relevant subject.
-Supervision and teaching of other researchers Chemistry, Biochemistry or Cell Biology Background
-Ability to communicate findings verbally and to write scientific reports to a high standard
-Excellent presentation skills Knowledge of Health and Safety procedures
Scholarship Open for International Students: Yes
Further Information: http://www.kcl.ac.uk/depsta/pertra/vacancy/external/pers_detail.php?jobindex=12271